Modification of mammary carcinogenesis and tissue peroxidation by selenium deficiency and dietary fat
- 1 January 1981
- journal article
- other
- Published by Taylor & Francis in Nutrition and Cancer
- Vol. 2 (3) , 136-142
- https://doi.org/10.1080/01635588109513673
Abstract
This study investigates the interdependence of selenium and unsaturated fat intake as modifiers of 1. the incidence of mammary tumors induced by 7, 12‐dimethylbenz (a) anthracene; and 2. the lability of mammary tissue to lipid peroxidation. Results suggest that there is an association between susceptibility of the mammary gland to carcinogenesis and its lability to peroxidation, and that both parameters are intimately regulated by fat intake in conjunction with the selenium status of the animal.Keywords
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