Determination of Serotonin Release from Platelets by Using A Serotonin-Selective Membrane Electrode
- 1 April 1987
- journal article
- analytical biochemistry-and-clinical-analysis
- Published by Taylor & Francis in Analytical Letters
- Vol. 20 (4) , 561-568
- https://doi.org/10.1080/00032718708067989
Abstract
A serotonin-selective membrane electrode was constructed for the first time by using sodium 2,4,6-trinitrobenzenesulfonate as an ion-exchanger and tris(2-ethylhexyl) phosphate as a membrane solvent, respectively, and was applied for the detection of thrombin-induced serotonin release from rabbit platelets. This method made it possible to monitor continuously the endogeneous serotonin secretion process from platelets in situKeywords
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