Specific hunger for thiamine: Recovery from deficiency and thiamine preference.

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Abstract
Young thiamine deficient rats were tested for thiamlne preference in a 2 choice (deficient vs. thiamine diet) situation with low or high vitamin concentration employed in different groups. Before the 10-day test period began most animals were injected with large amounts of thiamine, injections continuing regularly through the recovery and test period. Recovery periods ranged from 12 hr. to 10 days. Rats, partially or completely recovered from thiamine deficiency and having no need for thiamine, showed clear thiamine preference in similar proportion to deficient rats that needed thiamine. Control rats that had never been thiamine deficient showed no preference. Past history of thiamine deficiency seems a sufficient condition for the development of thiamine preference.

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