The Solubility of Methoxyflurane in Human Blood and Tissue Homogenates
Open Access
- 1 September 1963
- journal article
- research article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 24 (5) , 625-627
- https://doi.org/10.1097/00000542-196309000-00006
Abstract
Ostwald solubility coefficients of methoxyflurane were determined for various solvents. The values obtained were: for water, 4.50; blood, 13.0; oil, 825; muscle, 17.4; cerebral grey matter, 22.1; cerebral white matter, 30.9; and bovine hemoglobin, 106. These values correlate well with the clinical observation that methoxyflurane is extremely potent yet productive of a slow induction of, and slow recovery from, anesthesia.Keywords
This publication has 1 reference indexed in Scilit:
- Solubility of Diethyl Ether in Water, Blood and OilAnesthesiology, 1963