Evidence for the monomeric nature of thymosins
- 27 February 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 244 (2) , 287-290
- https://doi.org/10.1016/0014-5793(89)80547-2
Abstract
According to gel-filtration experiments, α- and β-thymosins appear to form oligomers, which are 4-5-fold larger than the corresponding polypeptides. However, on analysis by sedimentation equilibrium ultracentrifugation, prothymosin α and thymosin β4 showed relative molecular masses of 12 800 and 4600, which are close to the values calculated from their amino acid sequences, confirming their existence in solution as discrete monomeric entitiesKeywords
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