Warm IgM Anti‐IT Causing Autoimmune Haemolytic Anaemia
- 5 March 1977
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 32 (3) , 135-142
- https://doi.org/10.1111/j.1423-0410.1977.tb00618.x
Abstract
A patient with autoimmune hemolytic anemia due to an autoagglutinin of anti-IT specificity is reported. The antibody was of the Ig[immunoglobulin]M class and bound complement; unexpectedly, it reacted optimally at 37.degree. C. A prozone was noted when testing serial dilutions of the patient''s serum against appropriate red cells in saline, but was not found when testing an eluate prepared from the patient''s red cells. The prozone was probably due to a blocking antibody of high molecular weight, which appeared to be specific for I and IT.This publication has 18 references indexed in Scilit:
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