Enhanced avoidance behavior following septal lesions in the rat as a function of lesion size and spontaneous activity.

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Abstract
It is well established that large, bilateral lesions of the septal area in the rat facilitate acquisition of a shuttle-box avoidance response. In the present experiment it was found that this enhancement was just as pronounced with quite small and with unilateral septal lesions. Also rats with septal lesions did not show significantly more spontaneous activity as measured by operant rate of hurdle crossing before training or in the intertrial interval during training.