SP-1-Enzymimmunoassay: klinische Anwendung I. Schwangerschaftsfrühdiagnostik
- 1 June 1981
- journal article
- research article
- Published by Georg Thieme Verlag KG in Geburtshilfe und Frauenheilkunde
- Vol. 41 (06) , 404-406
- https://doi.org/10.1055/s-2008-1037187
Abstract
The enzyme immunologic determination of SP1 [.beta.-1-glycoprotein] in the serum is suitable for the early diagnosis of pregnancy from 14 days after ovulation onwards. In the control group of 64 nonpregnant women and of healthy men no SP1 was detected in the serum. At least 6 wk after the cessation of trophoplast activity SP1 can still be detected in the serum. The enzyme immunoassay technique of SP1 in the serum has a high sensitivity of 1 ng SP1/ml serum and a short measuring time of 2.5-4 h. This test is therefore excellent for the early diagnosis of pregnancy.Keywords
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