Low Birth Weight, Prematurity, and Postpartum Endometritis

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Abstract
We studied associations ofMycoplasma hominis, Ureaplasma urealyticum, andChlamydia trachomatisgenital infections with pregnancy outcomes, controlling by logistic and multiple linear regression for known risk factors and for the presence of the other two infections. A sample of 1204 Navajo women enrolling for prenatal care had endocervicalC trachomatis, M hominis, andU urealyticumcultures and serum samples taken at enrollment and when possible after 30 weeks. Low birth weight (1:32 on either sample or IgG seroconversion) were at greater risk of low birth weight (19% [3/16]) than women with chronic infection (4.5% [6/133]; relative risk, 4.2), this subgroup at risk was small (11% of women with classifiableC trachomatisinfection).Mycoplasma hominisandC trachomatisinfections may be important preventable causes of adverse pregnancy outcomes in identifiable subgroups of women. (JAMA1987;257:1189-1194)

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