Evaluation of Red Cell Damage During Cardiopulmonary Bypass
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Thoracic and Cardiovascular Surgery
- Vol. 19 (3) , 263-265
- https://doi.org/10.3109/14017438509102729
Abstract
In patients undergoing cardiopulmonary bypass (CPB), red cell damage was assessed by simultaneous measurement of plasma-hemoglobin (P-Hb) and red cell filtration rate (RFR) (1). RFR was significantly reduced after 120 min as compared with 30 min (17.4 .+-. 4.1 vs. 30.4 .+-. 2.9 .mu.l/s). P-Hb, by contrast, was significantly higher at 60 min than at 30 min after start of CPB (195 .+-. 27.2 vs. 73.8 .+-. 1 .mu.l/s). Significant negative correlation was found between RFR and P-Hb (r = 0.68). Red cell deformability thus permitted qualitative assessment of red cell trauma during CPB and thereby an estimation of the rheologic disturbance caused to these cells by CPB during open-heart surgery.This publication has 4 references indexed in Scilit:
- The Effect of Urea on Red Cell Deformability During Cardiopulmonary BypassScandinavian Journal of Thoracic and Cardiovascular Surgery, 1984
- Decreased Red Cell Deformability Following Open-Heart SurgeryScandinavian Journal of Thoracic and Cardiovascular Surgery, 1983
- Quantitative determination of plasma hemoglobin using dicarboxidineClinica Chimica Acta; International Journal of Clinical Chemistry, 1982
- Sublethal Damage to the Red Blood Cell from PumpingCirculation, 1967