Dialysis continuous process for ammonium lactate fermentation: Simulated prefermentor and cell‐recycling systems

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Abstract
A generalized mathematical model, previously developed and experimentally validated, was modified and used to computer‐simulate the outcomes of adding two systems for increasing the concentration of cell mass in the fermentor, and thereby the rate and extent of substrate conversion, in a dialysis continuous process for the ammonium lactate fermentation of deproteinized whey. The addition of a nondialysis continuous prefermentor would not improve the process. However, the addition of cell retention time would be reduced ninefold, and the extent of converting substrate to product would be increased 25% and accomplished almost entirely by maintenance metabolism.