Increased Oxygen Consumption of Liver and Kidney Slices in the Presence of Phenobarbital
- 28 February 1954
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 176 (3) , 468-470
- https://doi.org/10.1152/ajplegacy.1954.176.3.468
Abstract
The effects of phenobarbital Na on the O2 consumption of liver and kidney cortex slices of the rat were studied, using Warburg respirometers. There was a significant increase in O2 consumption rate of kidney cortex slices after tipping in 0.3 and 0.5 mg.% phenobarbital Na (P<0.003, and P< 0.008, respectively). Likewise there was an increase in O2 consumption rate of liver slices in the presence of 0.1 mg.% (P< 0.029), but not in the presence of 0.2, 0.3, and 0.5 mg.% phenobarbital.Keywords
This publication has 3 references indexed in Scilit:
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- EFFECTS OF PHENOBARBITAL ON OXYGEN CONSUMPTION OF BRAIN SLICES1949
- The effects of narcotics on tissue oxidationsBiochemical Journal, 1937