One-Pot Clean Synthesis of 1,8-Dioxo-decahydroacridines Catalyzed by p-Dodecylbenezenesulfonic Acid in Aqueous Media
- 13 July 2004
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 2004 (12) , 2001-2005
- https://doi.org/10.1055/s-2004-829151
Abstract
Reaction of aromatic aldehyde, 5,5-dimethyl-1,3-cyclohexanedione and p-toluidine in water were successfully carried out in the presence of p-dodecylbenezenesulfonic acid (DBSA) as a Brφnsted acid-surfactant-combined catalyst. This method provides several advantages such as environment friendliness, high yields and simple work-up procedure. In addition, water was chosen as a green solvent.Keywords
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