Relative carriage rates of nuclear dehydrogenating clostridia in two populations of different colorectal cancer risk

Abstract
Carriage of nuclear dehydrogenating clostridia has been associated with colon cancer and implicated in its etiology. The carriage of these organisms in a British population at high risk for the development of colon cancer was compared with a low risk Nigerian population. Clostridia were found in all of the stools from both populations. Nuclear dehydrogenating clostridia were only found in the stools of the British subjects (32%). The carriage rate of nuclear dehydrogenating clostridia in a population is probably related to the risk of colon cancer.

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