Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy
- 18 December 2001
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 12 (4) , 633-636
- https://doi.org/10.1016/s0960-894x(01)00814-9
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Synthesis and in vitro evaluation of iodine labelled pyrazolo[1,5-a]pyridines as highly selective dopamine D4 receptor ligandsJournal of Labelled Compounds and Radiopharmaceuticals, 2001
- Cyanoindole Derivatives as Highly Selective Dopamine D4Receptor Partial Agonists: Solid-Phase Synthesis, Binding Assays, and Functional ExperimentsJournal of Medicinal Chemistry, 2000
- Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD)Molecular Psychiatry, 2000
- The dopamine D4 receptor: A controversial therapeutic targetDrugs of the Future, 2000
- Azaindole derivatives with high affinity for the dopamine D4 receptor: Synthesis, ligand binding studies and comparison of molecular electrostatic potential mapsBioorganic & Medicinal Chemistry Letters, 1999
- 3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D4 ReceptorJournal of Medicinal Chemistry, 1996
- Dopamine D4 receptors elevated in schizophreniaNature, 1993
- A hypervariable segment in the human dopamine receptor D4 (DRD4) geneHuman Molecular Genetics, 1993
- Regioselective lithiation and reaction of [1,2,4]triazolo[1,5-a]pyridine and pyrazolo[1,5-a]pyridineThe Journal of Organic Chemistry, 1992
- Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapineNature, 1991