Abstract
A recent study1of 80 cases of carcinoma of the urinary bladder was made in order to determine the influence of the depth of mural infiltration on the five-year results following complete extirpation of the primary growth. Thirty-nine patients subjected to simple cystectomy and 41 to segmental resection (partial cystectomy) prior to Feb. 1, 1946, survived operation. Of 19 patients with tumors infiltrating less than halfway through the muscularis, 14 (74%) lived 5 to 14 years without evidence of recurrence or metastasis, whereas only 2 of 61 patients (3% ) with deeply invading tumors survived 5 years (Table 1). Moreover, only 10% of the patients with superficially infiltrating tumors died with evidence of extension of their vesical cancer, as compared with 85% of the patients with deep tumors. The histologic pattern and degree of cellular differentiation of each tumor, although indicating the potentiality of that tumor for rapid growth and

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