The dependence of postreplication repair on uvrB in a recF mutant of Escherichia coli K-12
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 155 (3) , 279-286
- https://doi.org/10.1007/bf00272806
Abstract
Mutants carrying recF143 or recF144 show wild type levels of host cell reactivation of UV-irradiated λvir and wild type rates of excision gap closure in repairing UV damage to their own DNA. The same mutants showed reduced rates of postreplication repair strand joining. When uvrA - recF- or uvrB - recF- strains are tested, postreplication repair strand joining is incomplete or does not occur at fluences above 1 J/m2. We suggest that there may be a UvrAB and a RecF pathway of postreplication repair or that the repair functions controlled or determined by uvrA uvrB and by recF may be similar. An intermediate in postreplication repair may accumulate in the uvr - recF- strain.This publication has 25 references indexed in Scilit:
- Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiationPublished by Elsevier ,2004
- Defective excision and postreplication repair of UV-damaged DNA in a recL mutant strain of E. coli K-12Molecular Genetics and Genomics, 1977
- Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.Proceedings of the National Academy of Sciences, 1976
- DNA gyrase: an enzyme that introduces superhelical turns into DNA.Proceedings of the National Academy of Sciences, 1976
- The effect of lexA and recF mutations on post-replication repair and DNA synthesis in Escherichia coli K-12Molecular Genetics and Genomics, 1975
- SOS Repair Hypothesis: Phenomenology of an Inducible DNA Repair Which is Accompanied by MutagenesisPublished by Springer Nature ,1975
- Persistence of pyrimidine dimers during post-replication repair in ultraviolet light-irradiated Escherichia coli K12Journal of Molecular Biology, 1974
- Genetic analysis of the recF pathway to genetic recombination in Escherichia coli k12: Isolation and characterization of mutantsJournal of Molecular Biology, 1973
- Repair of radiation-induced damage in Escherichia coli: I. Effect of rec mutations on post-replication repair of damage due to ultraviolet radiationJournal of Molecular Biology, 1970
- Parallel Behavior of F and P1 in Causing Indirect Induction of Lysogenic BacteriaCold Spring Harbor Symposia on Quantitative Biology, 1968