Association between exercise and quality of life in multiple myeloma cancer survivors

Abstract
The goal of this study was to examine the association between exercise and quality of life (QOL) in multiple myeloma cancer survivors. Using a retrospective design, 156 multiple myeloma cancer survivors were mailed a questionnaire that assessed self-reported exercise behavior over three periods (prediagnosis, active treatment, and off-treatment) and QOL. The response rate was 56% (88/156). Descriptive analyses indicated that 6.8% and 20.4% of survivors met national exercise guidelines during active and off-treatment periods, respectively. Exercise during active treatment and off-treatment were positively associated with overall QOL and all subdomains of QOL (all P<0.05) except physical wellbeing. A low percentage of multiple myeloma cancer survivors are exercising regularly either during active or off-treatment periods. Survivors who report more exercise during these periods also report higher QOL. These findings suggest that a randomized controlled trial is warranted.