Evaluation of villous patterns in tumors of the colon and rectum

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Abstract
Villous patterns can be found in adenomas, villous adenomas, papillomas, papillary adenocarcinomas and many neoplasms of the colon and rectum. Villous patterns were observed in 45% of adenomas in their series, usually occurring in large tumors, in the older age group, and associated with greater frequency when there was cellular atypia. Pedunculated forms may occur and, to make a diagnosis, microscopic as well as macroscopic criteria are essential. In villous adenoma there is a high incidence of malignant transformation and frequently these lesions are associated with separate benign or malignant tumors of the colon and rectum. In its pure form, villous papilloma is a tumor that is relatively rare and it behaves, essentially, like a villous adenoma. A negative biopsy does not exclude the possibility that malignant change may exist in another portion of a villous adenoma.

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