“Frozen” dynamic dimer model for transmembrane signaling in bacterial chemotaxis receptors
- 1 February 1994
- journal article
- review article
- Published by Wiley in Protein Science
- Vol. 3 (2) , 159-165
- https://doi.org/10.1002/pro.5560030201
Abstract
The crystal structures of the ligand binding domain of a bacterial aspartate receptor suggest a simple mechanism for transmembrane signaling by the dimer of the receptor. On ligand binding, one domain rotates with respect to the other, and this rotational motion is proposed to be transmitted through the membrane to the cytoplasmic domains of the receptor.Keywords
Funding Information
- National Institutes of Health (A130725)
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