Anti-Kappa/Lambda Immunobead for Detection of Human B Lymphocytes

Abstract
Several methods were compared for quantitating the B lymphocytes in human peripheral blood. REC rosette assays including sheep and bovine red blood cells, and immunobead rosette assays including beads coated with anti-KA and trivalent anti-GAM antibodies respectively were investigated. The anti-KA bead assay proved to be simpler, faster, higher in reproducibility, and appeared to be more accurate than any of the other assays.