Lead Poisoning

Abstract
Chronic Pb poisoning, especially in children, is a major medical problem, usually related to ingestion of leaded paint chips. In contrast with poisoning in children, Pb intoxication in adults is usually in the form of acute ingestions and is usually related to industrial exposure, but is occasionally due to ingestion of highly soluble Pb salts in illicit whiskey or "white-lightning", or from eating acidic foods which have leached the Pb out of improperly glazed ceramic containers. The occurrence of Pb intoxication, the absorption, metabolism and excretion of Pb, and diagnosis and treatment of Pb poisoning are discussed, and representative cases of Pb ingestion are presented. A number of specific therapeutic regimens, including dimercaprol, EDTA and D-penicillamine singly or in combination, are recommended for treating various degrees of Pb intoxication.

This publication has 21 references indexed in Scilit: