Synthesis and NK-2 antagonist effect of 1,6-diphenyl-pyrazolo [3,4-d]-thiazolo[3,2-a]4H-pyrimidin-4-one
- 9 January 1996
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 6 (1) , 59-64
- https://doi.org/10.1016/0960-894x(95)00558-b
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Potential of alkyl orthoformates as alkylating agents of non‐electron rich nitrogen heterocyclesJournal of Heterocyclic Chemistry, 1995
- Importance of Parallel Vectors and "Hydrophobic Collapse" of the Aligned Aromatic Rings: Discovery of a Potent Substance P AntagonistJournal of Medicinal Chemistry, 1994
- Influence of Lipophilicity on the Biological Activity of Cyclic Pseudopeptide NK-2 Receptor AntagonistsJournal of Medicinal Chemistry, 1994
- Functional mapping of the ligand binding sites of G-Protein coupled receptorsMedicinal Research Reviews, 1994
- Pyrazolothiazolopyrimidine derivatives as a novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluationEuropean Journal of Medicinal Chemistry, 1993
- Synthesis of 2,3,5,6,7,8-Hexahydro-3-amino-2-thioxo[1]benzothieno[2,3-d]pyrimidin-4(1H)-one and Derivatives of the New Heterocyclic System 7,8,9,10-Tetrahydro-3H,11H-[1]benzothieno[2',3':4,5]pyrimido[2,1-b][1,3,4]thiadiazin-11-oneHETEROCYCLES, 1993
- Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective .alpha.1 adrenoceptor ligandsJournal of Medicinal Chemistry, 1991
- Über neue Pyrazolverbindungen. IV Darstellung und Cyclisierungsverhalten einiger akzeptorsubstituierter N-(Pyrazol-3-yl)-thioharnstoffeJournal für Praktische Chemie, 1991
- Heilmittelchemische Studien in der heterocyclischen Reihe. 25. Mitteilung. Pyrazolo‐pyrimidine III Paraxanthin‐, Theobromin‐ und Theophyllin‐Analoga der Pyrazolo[3,4‐d]pyrimidin‐ReiheHelvetica Chimica Acta, 1959
- The Preparation and Hydrolysis of Mono- and Disubstituted Benzoylthioureas1Journal of the American Chemical Society, 1934