Plateletapheresis Using Single Vein Access: A Comparison of Haemonetics V‐50 and Fenwal CS‐3000 Blood Cell Separators

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Abstract
Donors were randomly selected for plateletapheresis using either the Haemonetics V-50 surge procedure or the Fenwal CS-3000 with special modifications. Six procedures using the V-50 were performed with 6 collection cycles. Platelet yields averaged 3.9 .times. 1011 with an average white cell contamination of 3.8 .times. 108. Ten procedures were performed with 8 collection cycles. Platelet yields averaged 4.5 .times. 1011 with an average white cell contamination of 1.2 .times. 108. CS-3000 procedures were performed using either 4,000 or 4,800 ml whole blood processed as the endpoint. Concentrates obtained using 4,000 ml (n = 10) as the endpoint contained 3.9 .times. 1011 platelets with a white cell contamination of 9.2 .times. 108. A 4,800 ml (n = 5) endpoint produced concentrates with a yield of 4.5 .times. 1011 and white cell contamination of 10.4 .times. 108.