A Comparative Study of the Analgesic and Anti-Inflammatory Activities of Pectolinarin Isolated fromCirsium subcoriaceumand Linarin Isolated fromBuddleia cordata
- 1 March 1998
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 64 (02) , 134-137
- https://doi.org/10.1055/s-2006-957390
Abstract
The dried aqueous extract of aerial parts of Cirsium subcoriaceum (Asteraceae) and its major flavonoid glycoside, pectolinarin, have been evaluated for analgesic and anti-inflammatory effects in mice and rats, respectively. Both the extract and pectolinarin exerted significant and dose-dependent analgesic and anti-inflammatory activities. Also, the anti-inflammatory activities of an aqueous extract of Buddleia cordata and its principal glycoside linarin were evaluated. The results of pharmacological testing proved that linarin is a better anti-inflammatory agent than pectolinarin and indomethacin. On the other hand, pectolinarin exerted a better analgesic effect than linarin.Keywords
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