Efficient Suzuki-Type Cross-Coupling of Enantiomerically Pure Cyclopropylboronic Acids
- 2 November 1998
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 37 (20) , 2845-2847
- https://doi.org/10.1002/(sici)1521-3773(19981102)37:20<2845::aid-anie2845>3.0.co;2-u
Abstract
Optically active cyclopropanes (e.g. 1) can be prepared by the use of tartaric acid derivatives as chiral auxiliaries in the palladium-catalyzed cross-coupling of optically active cyclopropylboronic acids with electrophiles. The absolute configuration of the chiral carbon atom is retained, and the reaction proceeds with good yields and enantiomeric excesses. R=H, p-Ph, o-CO2CH3, p-CO2CH3, p-NO2, o-OCH3, m-OCH3.This publication has 0 references indexed in Scilit: