THE NEPHROGRAM OF HEMORRHAGIC HYPOTENSION

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Abstract
The nephrogram intensity of excretory urography results from a combination of plasma hypaque concentration, glomerular filtration rate, and net urine flow. The prolonged nephrogram of hemorrhagic hypotension is the result of a continued but slow filtration of hypaque into a relatively static column of tubular fluid. Mannitol diuresis appears to be caused largely by its intratubular osmotic effect. The glomeruli continue slowly to filter a plasma that is rich in hypaque concentration, thus maintaining a prolonged nephrogram. THAM reverses the cortical ischemia of shock, and produces a clearance of hypaque from the plasma, urinary flow, and nephrogram sequence that simulate the normotensive control.

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