Reinnervation of spinal cord by cholinergic neurons.

Publisher Website
Google Scholar
Abstract
A technique is described by which ventral root fibers from the central end of the cut right L7 ventral root are caused to regenerate back into the cord through the central end of the cut left L7 dorsal root. The cats are allowed at least 8 weeks for recovery and regeneration before the lumbar area was reentered. At this time, stimulation of the grafted root resulted in facilitation and/or inhibition of a monosynaptic reflex at an adjacent segment. The grafted root could illicit a dorsal root reflex from the adjacent Lg dorsal root and the dorsal root of L6 could in turn illicit a dorsal root reflex in the grafted root but of a smaller amplitude. The anti-cholinesterase, eserine, potentiated the effects produced by graft stimulation and this effect could be counteracted by atropine. Continuity of the graft and the entry of the ventral root fibers into the cord dorsal root entry zone could be verified histologically.

This publication has 3 references indexed in Scilit: