EFFECT OF FUNDUSECTOMY ON THE ACIDITY OF THE GASTRIC AND DUODENAL CONTENT

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Abstract
Most surgical procedures for treatment of peptic ulcer are used in an endeavor to cause reduction in gastric acidity or in the length of time the ulcer is exposed to the gastric content. These results are brought about either by increasing the speed with which the stomach empties or by causing mixing of the alkaline duodenal sections with the gastric content through an altered or artificial stoma. In all probability few, if any. of the procedures employed affect directly the secretory mechanism involved in the production of hydrochloric acid. It would seem more logical in uncomplicated cases to perform some procedure which would reduce the ability of the stomach to produce hydrochloric acid. With this hypothesis in view experimental work was carried out on dogs in an effort to determine what effect removal of varying portions of acid-secreting mucous membrane has on the acidity of the gastric and duodenal content.

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