Enhancement of Encephalomyocarditis Virus Replication in L Cells Treated with Insulin
- 1 February 1981
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 166 (2) , 305-309
- https://doi.org/10.3181/00379727-166-41065
Abstract
Treatment of (mouse fibroblast) L cells with low levels of insulin results in a marked increase in the yield of encephalomyocarditis virus, strain MM. Maximum yields were obtained when the cell cultures were pretreated with the hormone for 24 h followed by the presence of insulin after virus infection. The increased virus yields cannot be attributed to increased cell proliferation or to interference with the interferon system.This publication has 5 references indexed in Scilit:
- Role of Interferon in the Antiviral State Elicited by Selected Interferon InducersExperimental Biology and Medicine, 1980
- Modulation of hexose uptake and insulin action by cell membrane fluidity. The effects of temperature on membrane fluidity, insulin action, and insulin binding.Journal of Biological Chemistry, 1979
- Gross structural changes in isolated liver cell plasma membranes upon binding of insulinBiochemistry, 1979
- Virus-induced diabetes mellitusArchiv für die gesamte Virusforschung, 1977
- Insulin effect on the cell cycle: analysis of the kinetics of growth parameters in confluent chick cells.Proceedings of the National Academy of Sciences, 1976