Thermal and Athermal Effects of Microwave Radiation on the Activity of Glucose-6-phosphate Dehydrogenase in Human Blood

Abstract
Human blood and yeast glucose-6-phosphate dehydrogenase were treated with 2.8 GHz microwave radiation (CW, 1 KHz square wave modulation) at an incident power density of between 500 mW/cm2 and 1000 mW/cm2. The power absorbed was observed to be 230 ± 70 mW/cm3. This corresponds to absorbed energies of 35 and 62 J/cm3 for the two treatment times used. Treatments were carried out at fixed temperatures of 37°, 46.7° and 49.7°C in such a way as to distinguish between thermal and athermal effects on the activity of glucose-6-phosphate dehydrogenase. Thermally induced reductions in relative activity of up to 80%, which were dependent on treatment period, were observed. The observed average athermal effect on the relative activity was (0.4 ± 1.8)%. This is not statistically significant, Thus no athermal effect of microwave radiation on the activity of glucose-6-phosphate dehydrogenase was observed.

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