Chromosomal Damage in Human Leukocytes Induced by Lysergic Acid Diethylamide
- 17 March 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 155 (3768) , 1417-1419
- https://doi.org/10.1126/science.155.3768.1417
Abstract
Addition of lysergic acid diethylamide to cultured human leukocytes resulted in a marked increase of chromosomal abnormalities. The distribution of chromosome breaks deviated significantly from random, with an accumulation of aberrations in chromosome No. 1. Cytogenetic investigation of a patient extensively treated with this drug over a 4-year period for paranoid schizophrenia showed a similar increase in chromosomal damage.This publication has 19 references indexed in Scilit:
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