Environmental Hydrocarbons Produce Degeneration in Cat Hypothalamus and Optic Tract
- 13 January 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 199 (4325) , 199-200
- https://doi.org/10.1126/science.413192
Abstract
2,5-Hexanedione, the principal neurotoxic metabolite of the industrial solvents n-hexane and methyl n-butyl ketone causes axonal degeneration in the mammillary body and visual nuclei of cats. Prolonged, low-level exposure to hydrocarbons in the environment may cause premature deterioration in areas of the human brain vital for perception and behavior.This publication has 8 references indexed in Scilit:
- Ultrastructural Studies of the Dying-Back ProcessJournal of Neuropathology and Experimental Neurology, 1977
- Ultrastructural Studies of the Dying-Back ProcessJournal of Neuropathology and Experimental Neurology, 1977
- Characterization of the metabolites of methyl n-butyl ketone, methyl iso-butyl ketone, and methyl ethyl ketone in guinea pig serum and their clearanceToxicology and Applied Pharmacology, 1976
- DEGENERATION IN CENTRAL AND PERIPHERAL NERVOUS SYSTEMS PRODUCED BY PURE n-HEXANE: AN EXPERIMENTAL STUDYBrain, 1976
- Glue sniffer's neuropathyNeurology, 1976
- Glue-Sniffing NeuropathyArchives of Neurology, 1975
- N-Hexane NeuropathyNew England Journal of Medicine, 1971
- Defect of memorizing of hippocampal-mammillary origin: a reviewJournal of Neurology, Neurosurgery & Psychiatry, 1963