Co‐cultivation of mast cells and FcɛRIα+ dendritic‐like cells from human hip bone marrow
- 21 February 2005
- journal article
- Published by Wiley in Clinical and Experimental Allergy
- Vol. 35 (2) , 226-233
- https://doi.org/10.1111/j.1365-2222.2005.02161.x
Abstract
Mast cells contribute to the pathogenesis of asthma and allergy through the release of a plethora of pro-inflammatory mediators and cytokines. Their study is hampered by the difficult access to human tissue samples. Human mast cells have been cultured from CD34+ progenitors in the bone marrow of normal volunteers following iliac crest bone marrow biopsy but this is invasive. Hip bone marrow could provide a more convenient less invasive source of mast cell progenitors.1513Keywords
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