STUDIES OF JOHNES DISEASE IN CANADA .11. COMPLEMENT-FIXATION TITRES + BLOOD CELL PICTURE

  • 1 January 1964
    • journal article
    • research article
    • Vol. 28  (10) , 248-+
Abstract
Complement-fixation titers and haemograms were determined monthly during a period of approximately 1 year for 9 cattle with Johne''s disease. Three of 4 experimentally infected animals died during the interval or shortly afterwards; all three developed high complement-fixing titers with Johne''s bacillus antigen. The experimentally infected animal that survived was serologically reactive for a few months, then became negative. One of the naturally infected cows exhibited a relatively high complement-fixing titer throughout but the other 4 were serologically negative or occasionally weekly reactive. All 9 cattle showed a variable degree of neutrophilia and lymphopaenia but an absolute eosinopaenia was observed only in the 3 that died.