Mechanism of Human Telomerase Inhibition by BIBR1532, a Synthetic, Non-nucleosidic Drug Candidate
Open Access
- 1 May 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (18) , 15566-15572
- https://doi.org/10.1074/jbc.m201266200
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- A highly selective telomerase inhibitor limiting human cancer cell proliferationThe EMBO Journal, 2001
- The Hallmarks of CancerCell, 2000
- Inhibition of telomerase limits the growth of human cancer cellsNature Medicine, 1999
- Telomere shortening and apoptosis in telomerase-inhibited human tumor cellsGenes & Development, 1999
- Creation of human tumour cells with defined genetic elementsNature, 1999
- Extension of Life-Span by Introduction of Telomerase into Normal Human CellsScience, 1998
- Human telomerase contains evolutionarily conserved catalytic and structural subunitsGenes & Development, 1997
- hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during ImmortalizationPublished by Elsevier ,1997
- A survey of telomerase activity in human cancerPublished by Elsevier ,1997
- A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesisNature, 1989