The Human Cytomegalovirus US10 Gene Product Delays Trafficking of Major Histocompatibility Complex Class I Molecules
Open Access
- 15 November 2002
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 76 (22) , 11753-11756
- https://doi.org/10.1128/jvi.76.22.11753-11756.2002
Abstract
Human cytomegalovirus (HCMV) US10 encodes a glycoprotein that binds to major histocompatibility complex (MHC) class I heavy chains. While expression of US10 delays the normal trafficking of MHC class I molecules out of the endoplasmic reticulum, US10 does not obviously facilitate or inhibit the action of two other HCMV-encoded MHC class I binding proteins, US2 and US11.Keywords
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