Nerve growth factor induces rapid redistribution of F‐actin in PC12 cells

Abstract
Nerve growth factor (NGF) induces the redistribution of F‐actin in rat pheochromocytoma PC12 cells within 2–10 min, whereas epidermal growth factor (EGF) has no effect on microfilament organization. This redistribution of F‐actin in PC12 cells is not protein synthesis dependent, but can be blocked by methyltransferase inhibitors.