Kinetic profiles of diacetoxyscirpenol and two of its metabolites in blood serum of pigs
- 1 April 1985
- journal article
- research article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 49 (4) , 842-845
- https://doi.org/10.1128/aem.49.4.842-845.1985
Abstract
Orally administered diacetoxyscirpenol (2 mg/kg of body weight) was rapidly absorbed into the blood serum of pigs; within 1 h, the highest amounts of diacetoxyscirpenol (9.6 to 21.9 ng/ml) were detected. Two metabolites of diacetoxyscirpenol were identified by gas chromatography-mass spectroscopy as monoacetoxyscirpenol and scirpenetriol. The three trichothecenes were present in the blood serum of pigs for only 24 h, indicating a rapid metabolism of these compounds.This publication has 17 references indexed in Scilit:
- Gas chromatographic method for the determination of diacetoxyscirpenol in swine plasma and urineJournal of Chromatography A, 1982
- Metabolic fate of T-2 toxin in a lactating cowFood and Cosmetics Toxicology, 1981
- Distribution of tritium-labeled T-2 toxin in swineJournal of Agricultural and Food Chemistry, 1979
- Toxic Substances Produced by Fusarium V: Occurrence of Zearalenone, Diacetoxyscirpenol, and T-2 Toxin in Moldy Corn Infected with Fusarium moniliforme Sheld.Journal of Pharmaceutical Sciences, 1978
- Natural occurrence of trichothecenes (nivalenol, deoxynivalenol, T2) and zearalenone in cornCellular and Molecular Life Sciences, 1978
- Necrotic Oral Lesions in Chickens Fed Diacetoxyscirpenol, T—2 Toxin, and CrotocinPoultry Science, 1978
- Two new trichothecenes produced by Fusarium roseumJournal of Agricultural and Food Chemistry, 1978
- [Fusarium toxins].1977
- Monoacetoxyscirpenol. New mycotoxin produced by Fusarium roseum GibbosumJournal of Agricultural and Food Chemistry, 1976
- The cytotoxicity of some transformation products of diacetoxyscirpenolBiochemical Pharmacology, 1969