The Effect of Certain Steroids Upon the Growth of Trichophyton rubrum
- 1 July 1962
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 28 (3) , 437-441
- https://doi.org/10.1099/00221287-28-3-437
Abstract
SUMMARY: The effect of thirty-seven different steroids on the growth of Trichophyton rubrum is reported. The effects varied from complete inhibition of growth to stimulation. Highly inhibitory compounds included androstan-3, 17-dione, testosterone, 11-deoxycorticosterone, progesterone and 7-dehydro-cholesterol. 17α-Hydroxypregnenolone was stimulatory but all other compounds with the 17α-hydroxyl group were inactive. Structural requirements for activity are discussed.Keywords
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