REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES
- 1 December 1963
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 50 (6) , 1026-1032
- https://doi.org/10.1073/pnas.50.6.1026
Abstract
Repressed and active chromatin can be isolated in mass from interphase calf thymus lymphocytes. Up to 80% of interphase lymphocyte DNA is found in the repressed chromatin fraction. Repressed interphase DNA appears as condensed (hetero-)chromatin, while active interphase DNA appears as extended (eu-)chromatin fibrils. The extended (eu-) chromatin fraction contains the bulk of the rapidly labeled RNA of the nucleus.Keywords
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