Interaction of mitochondrial creatine kinase with model membranes A monolayer study
Open Access
- 9 April 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 281 (1-2) , 123-129
- https://doi.org/10.1016/0014-5793(91)80374-c
Abstract
The interaction of mitochondrial creatine kinase (Mi‐CK; EC 2.7.3.2) with phospholipid monolayers and spread mitochondrial membranes at the air/water interface has been investigated. It appeared that Mi‐CK penetrated into these monolayers as evidenced by an increase in surface pressure upon incorporation of Mi‐CK. The increase in surface pressure was dependent on (1) the amount and (2) the oligometric form of Mi‐CK in the subphase, as well as on (3) the initial surface pressure and (4) the phospholipid composition of the monolayer. In this experimental system Mi‐CK was able to interact equally well with both inner and outer mitochondrial membranes.Keywords
This publication has 32 references indexed in Scilit:
- The role of contact sites between inner and outer mitochondrial membrane in energy transferBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1990
- A spin‐label electron spin resonance study of the binding of mitochondrial creatine kinase to cardiolipinEuropean Journal of Biochemistry, 1989
- Further characterization of contact sites from mitochondria of different tissues: topology of peripheral kinasesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1989
- Ultrastructural localisation of creatine kinase activity in the contact sites between inner and outer mitochondrial membranes of rat myocardiumBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1989
- Mitochondrial protein importBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989
- Heart mitochondria in physiological salt solution: Not ionic strength but salt composition is important for association of creatine kinase with the inner membrane surfaceBiochemical and Biophysical Research Communications, 1986
- Lipids of mitochondriaBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1985
- Further studies on the spreading of biomembranes at the air/water interface Structure, composition, enzymatic activities of human erythrocyte and sarcoplasmic reticulum membrane filmsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1981
- The enzymatic synthesis of phosphatidylserine and purification by CM-cellulose column chromatographyBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1977
- Relation between various phospholipase actions on human red cell membranes and the interfacial phospholipid pressure in monolayersBiochimica et Biophysica Acta (BBA) - Biomembranes, 1975