Prophylactic Treatment for Rabies by Means of Standardized Glycerinated Virus

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Abstract
In a previous article (1) we compared the various antirabic methods, discussed their gradual evolution from the crude procedure employed by Pasteur to a much more accurate and, judging from our experience, more efficient technic—that is, the use of a “standardized” virus in such a form that it can be preserved with practically unchanged virulence, for a long period of time. The Harris (2) method of desiccating and preserving fixed virus is almost ideal from the standpoint of therapeutic efficiency, but it is cumbersome and complicated by many manipulations which afford opportunities for accidental contamination of the virus during its preparation. The number of living infectious units in the finished product is also greatly affected by any variation in the rapidity of drying; as a result, after standardization and sterility tests have been made, much of the material prepared with so great effort, must be discarded.

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