VENTILATION-PERFUSION RELATIONSHIPS

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Abstract
The principles governing gas exchange in a single human lung unit are examined and the clinical assessment of ventilation-perfusion inequality is briefly discussed. The behavior of distributions of ventilation-perfusion ratios, the measurement of these distributions and typical patterns seen in several types of lung disease and also considered in this review. The principles of ventilation-perfusion relationships as a basis for understanding the impairment of gas exchange in lung disease are emphasized.