SOME ALDOSTERONE‐PRODUCING ADRENAL TUMOURS ALSO SECRETE CORTISOL, BUT PRESENT CLINICALLY AS PRIMARY ALDOSTERONISM
- 1 March 1990
- journal article
- Published by Wiley in Clinical and Experimental Pharmacology and Physiology
- Vol. 17 (3) , 167-171
- https://doi.org/10.1111/j.1440-1681.1990.tb01300.x
Abstract
1. Two patients with angiotensin-responsive aldosterone-producing adenoma (APA) and one with adrenal cortical carcinoma demonstrated autonomous secretion of cortisol as well as of aldosterone. 2. The response of cortisol and of aldosterone to ACTH did not differentiate between the two APA which secreted cortisol and the eight which demonstrated normal suppression with dexamethasone. 3. Concurrent autonomous secretion of cortisol as well as aldosterone may occur in patients who present clinically with primary aldosteronism. 4. Biochemical distinctions between adenomas may reflect differences in their cellular composition.Keywords
This publication has 11 references indexed in Scilit:
- Primary HyperaldosteronismMedical Clinics of North America, 1988
- Glucocorticoid-Suppressible Aldosteronism: A Disorder of the Adrenal Transitional Zone*Journal of Clinical Endocrinology & Metabolism, 1988
- ADRENAL TRANSITIONAL ZONE STEROIDS, 18‐OXO AND 18‐HYDROXYCORTISOL, USEFUL IN THE DIAGNOSIS OF PRIMARY ALDOSTERONISM, ARE ACTH‐DEPENDENTClinical and Experimental Pharmacology and Physiology, 1988
- Hyperaldosteronism combined with hypercortisolaemia in a patient with adrenal carcinomaPublished by Oxford University Press (OUP) ,1988
- Aldosterone-Producing Adrenocortical CarcinomaAnnals of Internal Medicine, 1984
- In vivo evidence of cortisol secretion by aldosterone-producing adenomasActa Endocrinologica, 1984
- Primary aldosteronism due to adrenal carcinomasJournal of Molecular Medicine, 1984
- Hormone and Blood Pressure Relationships in Primary AldosteronismClinical and Experimental Hypertension. Part A: Theory and Practice, 1984
- Concurrent hypersecretion of aldosterone and cortisol from the adrenal cortical adenomaThe American Journal of Medicine, 1979
- Concurrent hypercortisolism and hypermineralocorticoidismThe American Journal of Medicine, 1977