Effect of Alpha-lnterferon on Erythrocyte and Hepatocyte Plasma Membranes Derived from Cirrhotic Rats
- 1 January 1994
- journal article
- research article
- Published by S. Karger AG in Pharmacology
- Vol. 48 (1) , 63-68
- https://doi.org/10.1159/000139163
Abstract
Interferons are recognized to inhibit collagen production. Since fibrosis has been associated with liver dysfunction, we investigated the effects of α-interferon on the function and lipid composition of hepatocyte and erythrocyte plasma membranes derived from CCU-cirrhotic male Wistar rats. In both cell types, CCI4 decreased Na+/K+ and Ca2+-ATPase activity and increased the cholesterol to phospholipids (CH/PL) ratio (pKeywords
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