Naltrexone Treatment for Alcohol Dependence

Abstract
Treatment for alcohol dependence has been limited almost entirely to various types of counseling. An exception has been the use of the medication disulfiram, which acts indirectly by making a person feel ill if he or she drinks alcohol. The efficacy of disulfiram is limited, however, because compliance is often poor, and it is not widely used.Counseling patients with alcoholism leads to rates of remission similar to those achieved with treatment of other chronic medical conditions, such as asthma.1 Nonetheless, the large number of people dependent on alcohol in the United States (over 8.1 million2) and the substantial . . .