The Usefulness of Cell Surface Markers in Predicting the Prognosis of Non-Hodgkin's Lymphomas
- 1 January 1993
- journal article
- research article
- Published by Taylor & Francis in Critical Reviews in Clinical Laboratory Sciences
- Vol. 30 (1) , 1-28
- https://doi.org/10.3109/10408369309084664
Abstract
The Working Formulation for classification of non-Hodgkin's lymphomas provides useful prognostic information. Since this scheme was published in 1982, many studies have investigated the prognostic significance of various cell surface markers in lymphoma cases. This article reviews the value of distinguishing T cells from B cells, CDS+ B cells, immunoglobulin light chain types, proliferation antigens such as Ki 67, other markers of B-cell differentiation, and chromosomal anomalies. Each of these contributes some further prognostic significance to that already determined by the Working Formulation.Keywords
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