Paralytic Shellfish Poison and Melanin Distribution in Fractions of Toxic Butter Clam (Saxidomus giganteus) Siphon

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Abstract
Frozen toxic butter clam (Saxidomus giganteus) siphons were fractionated and each fraction was bioassayed for paralytic shellfish poison (PSP) and chemically analyzed for melanin. Sonication removed over 50% of the melanin from the siphons and this fraction contained nearly 50% of the PSP initially present in the siphons. The data presented further implicate melanin as a PSP binding agent in vivo.

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