CORRELATION OF MATERNAL SERUM C-REACTIVE PROTEIN WITH OUTCOME OF TOCOLYSIS

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  • 1 January 1984
    • journal article
    • research article
    • Vol. 63  (2) , 220-224
Abstract
Subclinical intrauterine infection is an important cause of preterm labor, specifically where tocolysis has failed. Patients (50) in preterm labor with singleton pregnancies were studied prospectively to determine whether the presence or absence of C-reactive protein, a nonspecific marker for [bacterial] infection, would correlate with success or failure of tocolysis. Of the 50 patients, tocolysis failed in 11 of 15 women with a positive C-reactive protein determination. Tocolysis succeeded in 33 of 35 cases where C-reactive protein was negative (P < 0.0005). Urinary tract infection occurred in 40% of the study patients, but was not a confounding factor in the interpretation of C-reactive protein.